Chris Bakal: Look and learn
نویسنده
چکیده
JCB • VOLUME 203 • NUMBER 3 • 2013 378 W hat can you learn about a cell just by looking at it? Quite a lot, as it turns out. A cell’s shape can tell you about its behavior and its function in the body, just for a start. And, as Chris Bakal can attest, a cell’s shape can also tell you a lot about the signaling pathways at work. Bakal has been interested in cellular signaling pathways ever since his undergraduate days (1), but his approach to studying them (2) has evolved considerably over time (3–5). Today, in his lab at London’s Institute of Cancer Research, Bakal’s lab members use computational neural networks and advanced statistical methods to identify and analyze cellular features that inform us about signaling networks. We called him to learn about this approach to studying cell shape and to get a wider view of his career.
منابع مشابه
A direct look at RNAi screens
Dynamical Cell Systems Laboratory, Division of Cancer Biology, Chester Beatty Laboratories, Institute of Cancer Research, London, UK * Corresponding author. Dynamical Cell Systems Laboratory, Division of Cancer Biology, Chester Beatty Laboratories, Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK. Tel.: þ 44 20 7153 5080; Fax: þ 44 20 7153 5177; E-mail: E-mail: chris.bakal@icr....
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